BDBM50136432 2-(1-Methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-ylcarbamoyl)-1H-indole-5-carboxylic acid methyl ester::CHEMBL136188

SMILES COC(=O)c1ccc2[nH]c(cc2c1)C(=O)NC1Cc2ccccc2N(C)C1=O

InChI Key InChIKey=IONIWZRSZHTCFY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136432   

TargetGlycogen phosphorylase, liver form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136432(2-(1-Methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibitory concentration against recombinant human liver glycogen phosphorylase a (HLGPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen phosphorylase, muscle form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136432(2-(1-Methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory concentration against recombinant human muscle glycogen phosphorylase a (HMGPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50136432(2-(1-Methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human liver glycogen phosphorylase 1a assessed as release of phosphate from glucose-1- phosphate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed