BDBM50136571 CHEMBL3752830

SMILES CCCc1ccc(C[C@H](NC(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)C(=O)Nc2ccc(cc2)C(O)=O)cc1

InChI Key InChIKey=ZOYNBBLZWSJHEP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50136571   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50136571(CHEMBL3752830)
Affinity DataKi:  7.10nMAssay Description:Inhibition of human coagulation factor 11a assessed as substrate hydrolysis to p-nitroaniline incubated for 10 to 120 mins by spectrophotometry analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2017
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50136571(CHEMBL3752830)
Affinity DataKi:  804nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2017
Entry Details Article
PubMed