BDBM50136587 3-((3R,4R)-3,4-Dimethyl-1-quinolin-2-ylmethyl-piperidin-4-yl)-benzamide::CHEMBL337341

SMILES C[C@H]1CN(Cc2ccc3ccccc3n2)CC[C@@]1(C)c1cccc(c1)C(N)=O

InChI Key InChIKey=SYACNGUASVLLLQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136587   

TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136587(3-((3R,4R)-3,4-Dimethyl-1-quinolin-2-ylmethyl-pipe...)
Affinity DataKi:  8nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136587(3-((3R,4R)-3,4-Dimethyl-1-quinolin-2-ylmethyl-pipe...)
Affinity DataKi:  220nMAssay Description:Inhibition of [3H]diprenorphine binding to the cloned human delta opioid receptors using 10 uM concentration of the compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50136587(3-((3R,4R)-3,4-Dimethyl-1-quinolin-2-ylmethyl-pipe...)
Affinity DataKi:  600nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed