BDBM50136711 (S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3,3-dimethyl-2-[(1-methyl-1H-pyrrol-2-ylmethyl)-amino]-butan-1-one::CHEMBL140547

SMILES COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H](NCc1cccn1C)C(C)(C)C

InChI Key InChIKey=PQFAHNADQUUXGS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50136711   

TargetOrexin receptor type 2(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136711((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration against human orexin-2 receptor (hOX2R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50136711((S)-1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibitory concentration against human orexin-1 receptor (hOX1R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed