BDBM50136722 4-(1-Benzhydryl-5-bromo-1H-indol-3-ylmethyl)-3-methoxy-benzoic acid::CHEMBL140539

SMILES COc1cc(ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12)C(O)=O

InChI Key InChIKey=FECNHWUMLHYCRX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136722   

TargetCytosolic phospholipase A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50136722(4-(1-Benzhydryl-5-bromo-1H-indol-3-ylmethyl)-3-met...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against cystolic phospholipase A2 alpha receptor (c-PLA2 alpha) using coumarin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50136722(4-(1-Benzhydryl-5-bromo-1H-indol-3-ylmethyl)-3-met...)
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against LTB4 receptor determined in human neutrophils PMN assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50136722(4-(1-Benzhydryl-5-bromo-1H-indol-3-ylmethyl)-3-met...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration against LTB4 receptor determined in mast cell line MC-9 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed