BDBM50137174 (1H-Indol-5-yl)-(6-thiophen-2-yl-thieno[3,2-d]pyrimidin-4-yl)-amine::CHEMBL76751

SMILES N(c1ccc2[nH]ccc2c1)c1ncnc2cc(sc12)-c1cccs1

InChI Key InChIKey=YXIIIHIHDBMOTL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50137174   

TargetEpidermal growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137174((1H-Indol-5-yl)-(6-thiophen-2-yl-thieno[3,2-d]pyri...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137174((1H-Indol-5-yl)-(6-thiophen-2-yl-thieno[3,2-d]pyri...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50137174((1H-Indol-5-yl)-(6-thiophen-2-yl-thieno[3,2-d]pyri...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50137174((1H-Indol-5-yl)-(6-thiophen-2-yl-thieno[3,2-d]pyri...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed