BDBM50137193 CHEMBL79215::N*4*-(1H-Indol-5-yl)-N*6*-(2-phenylamino-ethyl)-N*6*-pyrrol-1-yl-thieno[3,2-d]pyrimidine-4,6-diamine

SMILES C(CN(c1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2s1)n1cccc1)Nc1ccccc1

InChI Key InChIKey=TUGBVZCJQUNZOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137193   

TargetEpidermal growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137193(N*4*-(1H-Indol-5-yl)-N*6*-(2-phenylamino-ethyl)-N*...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50137193(N*4*-(1H-Indol-5-yl)-N*6*-(2-phenylamino-ethyl)-N*...)
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed