BDBM50137286 6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide::CHEMBL356124

SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)ccc2C1C(=O)NO

InChI Key InChIKey=ZJOQXNGTEXFLLO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50137286   

TargetMatrix metalloproteinase-9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of matrix metalloprotease-14 (MMP-14)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-15(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 621nMAssay Description:Inhibition of matrix metalloprotease-15 (MMP-15)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-26(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 7.51E+3nMAssay Description:Inhibition of matrix metalloprotease-26 (MMP-26)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 7.69E+3nMAssay Description:Inhibition of matrix metalloprotease-12 (MMP-12)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 724nMAssay Description:Inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed