BDBM50137549 5-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cyclopropyl]-1H-imidazole::CHEMBL52345

SMILES CC1(C)[C@@H]([C@H]1c1cc(Cl)cc(Cl)c1)c1cnc[nH]1

InChI Key InChIKey=OJGHXYKAHUKLJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137549   

TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50137549(5-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cy...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed