BDBM50137554 5-[(1R,3S)-3-(3-Chloro-phenyl)-2,2-dimethyl-cyclopropyl]-thiazol-2-ylamine::CHEMBL50671

SMILES CC1(C)[C@@H]([C@H]1c1cccc(Cl)c1)c1cnc(N)s1

InChI Key InChIKey=LQOFYQTYKRHYNC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137554   

TargetSodium/hydrogen exchanger 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50137554(5-[(1R,3S)-3-(3-Chloro-phenyl)-2,2-dimethyl-cyclop...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed