BDBM50137695 (S)-4-(S)-Hydroxy-5-[(S)-2-((2S,3S)-2-hydroxy-3-methyl-pentanoylamino)-4-methyl-pentanoylamino]-2-isobutyl-6-phenyl-hexanoic acid {(S)-2-methyl-1-[(pyridin-4-ylmethyl)-carbamoyl]-propyl}-amide::CHEMBL280244

SMILES CC[C@H](C)[C@H](O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCc1ccncc1

InChI Key InChIKey=XKMKASCTPIXULN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137695   

TargetBeta-secretase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50137695((S)-4-(S)-Hydroxy-5-[(S)-2-((2S,3S)-2-hydroxy-3-me...)
Affinity DataIC50: 176nMAssay Description:In vitro inhibitory activity against Beta-secretase 1 in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed