BDBM50137834 6-(2,4-Dioxo-1,4-dihydro-2H-quinazolin-3-yl)-hexanoic acid (2-amino-phenyl)-amide::CHEMBL327924

SMILES Nc1ccccc1NC(=O)CCCCCn1c(=O)[nH]c2ccccc2c1=O

InChI Key InChIKey=UZPTVMKSHYHDNT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137834   

TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137834(6-(2,4-Dioxo-1,4-dihydro-2H-quinazolin-3-yl)-hexan...)
Affinity DataIC50: 4.00E+3nMAssay Description:Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50137834(6-(2,4-Dioxo-1,4-dihydro-2H-quinazolin-3-yl)-hexan...)
Affinity DataEC50:  1.00E+4nMAssay Description:Effect on induced hyperacetylation of histones in whole cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed