BDBM50137875 4-[2-(3-Cyano-propoxy)-phenyl]-2,4-dioxo-butyric acid::4-[2-(3-cyanopropoxy)phenyl]-2,4-dioxobutanoic acid::CHEMBL175171::CHEMBL196154

SMILES OC(=O)C(=O)CC(=O)c1ccccc1OCCCC#N

InChI Key InChIKey=OZSGEZVVXJEIDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137875   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50137875(CHEMBL175171 | CHEMBL196154 | 4-[2-(3-cyanopropoxy...)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50137875(CHEMBL175171 | CHEMBL196154 | 4-[2-(3-cyanopropoxy...)
Affinity DataIC50: 380nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed