BDBM50137982 7-Chloro-9-(4-methyl-[1,4]diazepan-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL177455

SMILES CN1CCCN(CC1)C1=Cn2cccc2Sc2ccc(Cl)cc12

InChI Key InChIKey=FALNVJOEUBWZEU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50137982   

TargetD(2) dopamine receptor(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50137982(7-Chloro-9-(4-methyl-[1,4]diazepan-1-yl)-4-thia-10...)
Affinity DataKi:  3.5nMAssay Description:In vitro binding affinity towards Dopamine receptor D2 in rat tissue homogenate using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50137982(7-Chloro-9-(4-methyl-[1,4]diazepan-1-yl)-4-thia-10...)
Affinity DataKi:  4.30nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 2A receptor in rat tissue homogenate using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50137982(7-Chloro-9-(4-methyl-[1,4]diazepan-1-yl)-4-thia-10...)
Affinity DataKi:  4.30nMAssay Description:In vitro binding affinity towards Dopamine receptor D3 in Sf9 cell membranes using [3H]7-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50137982(7-Chloro-9-(4-methyl-[1,4]diazepan-1-yl)-4-thia-10...)
Affinity DataKi:  5.90nMAssay Description:In vitro binding affinity towards Dopamine receptor D1 in rat tissue homogenate using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2012
Entry Details Article
PubMed