BDBM50138158 CHEMBL3752854

SMILES COc1ccc(cc1)-c1cncc(c1)-c1ccc(cc1)C(N)=O

InChI Key InChIKey=FGGKGCUTYJQVJX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138158   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50138158(CHEMBL3752854)Copy SMILESCopy InChI

Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/25/2017
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50138158(CHEMBL3752854)Copy SMILESCopy InChI

Affinity DataIC50: 600nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/25/2017
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL