BDBM50138221 CHEMBL3752627

SMILES C[C@H]1CC=C(C(O)=O)[C@@](C)(C1)c1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=DHXALSJOFDCOHZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138221   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50138221(CHEMBL3752627)
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]MCP-1 from CCR2 in human PBMC by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50138221(CHEMBL3752627)
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]MCP-1 from CCR2 in human PBMC by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50138221(CHEMBL3752627)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced inhibition of calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50138221(CHEMBL3752627)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced inhibition of chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed