BDBM50138471 3-(3,4-Dichloro-phenyl)-8-((S)-8-methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-8-aza-bicyclo[3.2.1]oct-2-ene::CHEMBL149776

SMILES COc1cccc2OC[C@H](CN3C4CCC3C=C(C4)c3ccc(Cl)c(Cl)c3)Oc12

InChI Key InChIKey=BHOQAPSNFDJZNW-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50138471   

TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50138471(3-(3,4-Dichloro-phenyl)-8-((S)-8-methoxy-2,3-dihyd...)
Affinity DataKi:  4.70nMAssay Description:Inhibitory activity of compound against serotonin transport by RB5-5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50138471(3-(3,4-Dichloro-phenyl)-8-((S)-8-methoxy-2,3-dihyd...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity of compound against serotonin transport by HC5-5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50138471(3-(3,4-Dichloro-phenyl)-8-((S)-8-methoxy-2,3-dihyd...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed