BDBM50138472 (1R,3R,5S)-3-Benzo[b]thiophen-3-yl-8-((S)-8-ethoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-8-aza-bicyclo[3.2.1]octan-3-ol::CHEMBL344745

SMILES CCOc1cccc2OC[C@H](CN3[C@H]4CC[C@@H]3C[C@](O)(C4)c3csc4ccccc34)Oc12

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138472   

Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50138472((1R,3R,5S)-3-Benzo[b]thiophen-3-yl-8-((S)-8-ethoxy...)
Affinity DataKi:  17nMAssay Description:Agonistic activity of compound towards 5-hydroxytryptamine 1A receptor was evaluated by [35S]GTP-gamma-S, stimulated cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50138472((1R,3R,5S)-3-Benzo[b]thiophen-3-yl-8-((S)-8-ethoxy...)
Affinity DataKi:  124nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed