BDBM50138475 8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-3-naphthalen-1-yl-8-aza-bicyclo[3.2.1]oct-2-ene::CHEMBL356904

SMILES COc1cccc2OC[C@H](CN3C4CCC3C=C(C4)c3cccc4ccccc34)Oc12

InChI Key InChIKey=ZIQRGFPFGAMDTI-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50138475   

TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50138475(8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl...)
Affinity DataKi:  26nMAssay Description:Inhibitory activity of compound against serotonin transport by RB5-5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50138475(8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl...)
Affinity DataKi:  357nMAssay Description:Agonistic activity of compound towards 5-hydroxytryptamine 1A receptor was evaluated by [35S]GTP-gamma-S, stimulated cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50138475(8-((S)-8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl...)
Affinity DataIC50: 951nMAssay Description:Inhibitory activity of compound against serotonin transport by HC5-5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed