BDBM50138514 1-(3,4-Dichloro-benzyl)-3-(7-hydroxy-naphthalen-1-yl)-urea::CHEMBL358953

SMILES Oc1ccc2cccc(NC(=O)NCc3ccc(Cl)c(Cl)c3)c2c1

InChI Key InChIKey=FVDRRMNYXKAFMY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138514   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50138514(1-(3,4-Dichloro-benzyl)-3-(7-hydroxy-naphthalen-1-...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards cloned human vanilloid receptor subtype 1 in HEK293 cell membranes using [3H]RTX as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50138514(1-(3,4-Dichloro-benzyl)-3-(7-hydroxy-naphthalen-1-...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]-RTX binding to human vanilloid receptor subtype 1 expressed in HEK293 cell membranes (inactive)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed