BDBM50138517 1,1-Dibenzyl-3-(7-hydroxy-naphthalen-1-yl)-urea::CHEMBL151657

SMILES Oc1ccc2cccc(NC(=O)N(Cc3ccccc3)Cc3ccccc3)c2c1

InChI Key InChIKey=SRFWKKYRWZKFDE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138517   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50138517(1,1-Dibenzyl-3-(7-hydroxy-naphthalen-1-yl)-urea | ...)
Affinity DataKi:  3.28E+3nMAssay Description:Binding affinity towards cloned human vanilloid receptor subtype 1 in HEK293 cell membranes using [3H]RTX as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50138517(1,1-Dibenzyl-3-(7-hydroxy-naphthalen-1-yl)-urea | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Increased [Ca2+] influx in HEK293 cell membranes expressing human vanilloid receptor subtype 1 (inactive)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed