BDBM50138741 (3-(4-chlorophenyl)-5-(2,2,2-trifluoroethylthio)-1H-1,2,4-triazol-1-yl)(piperidin-1-yl)methanone::CHEMBL130628::[3-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethylsulfanyl)-[1,2,4]triazol-1-yl]-piperidin-1-yl-methanone

SMILES FC(F)(F)CSc1nc(nn1C(=O)N1CCCCC1)-c1ccc(Cl)cc1

InChI Key InChIKey=GTBUYLWBDILEPY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138741   

TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138741([3-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethylsulfa...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138741([3-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethylsulfa...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138741([3-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethylsulfa...)
Affinity DataIC50: 400nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138741([3-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethylsulfa...)
Affinity DataIC50: 7.06nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed