BDBM50138781 (1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-methyl-cyclopropanecarboxylic acid::2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarboxylic acid::CHEMBL334160

SMILES C[C@@H]1[C@H]([C@H](N)C(O)=O)[C@H]1C(O)=O

InChI Key InChIKey=ZLKKUEAUAXFRAV-UHFFFAOYSA-N

Data  11 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50138781   

TargetMetabotropic glutamate receptor 1(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu1 receptor expressed in CHO cells assessed as myo-[2-3H]Inositol turnover by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 7 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 1 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 5 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 4 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50:  1.32E+3nMAssay Description:Metabotropic glutamate receptor 8 agonist activity against forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50:  38nMAssay Description:Metabotropic glutamate receptor 3 agonist activity against forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50:  1.20E+3nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50:  8nMAssay Description:Metabotropic glutamate receptor 2 agonist activity against forskolin stimulated c-AMP formation in rat non neuronal cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50: >10nMAssay Description:Agonist activity at mGlu2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50138781(2-(Amino-carboxy-methyl)-3-methyl-cyclopropanecarb...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu4 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed