BDBM50139428 CHEMBL3765551

SMILES COc1cc(OC)c2c(c1)oc(cc2=O)N1CCN(Cc2ccccc2[N+]([O-])=O)CC1

InChI Key InChIKey=RFXSZHBPXJRMRH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139428   

TargetMultidrug resistance-associated protein 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50139428(CHEMBL3765551)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human MRP1 transfected in MDCK2 cells assessed as inhibition of calcein-AM effluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50139428(CHEMBL3765551)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ABCB1 in human KBV1 cells assessed as inhibition of calcein-AM effluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50139428(CHEMBL3765551)
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells by Hoechst 33342 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed