BDBM50139443 CHEMBL3765024

SMILES COc1cc(OC)c2c(c1)oc(cc2=O)N1CCN(CCc2ccc(cc2)[N+]([O-])=O)CC1

InChI Key InChIKey=GUOUAMXYOJDXCN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139443   

TargetMultidrug resistance-associated protein 1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50139443(CHEMBL3765024)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human MRP1 transfected in MDCK2 cells assessed as inhibition of calcein-AM effluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50139443(CHEMBL3765024)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of ABCB1 in human KBV1 cells assessed as inhibition of calcein-AM effluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50139443(CHEMBL3765024)
Affinity DataIC50: 3.69E+4nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells by Hoechst 33342 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed