BDBM50139452 CHEMBL3764943

SMILES Fc1ccc(cc1)-c1c(cnc2cc(F)ccc12)S(=O)(=O)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=ZNJHGNQUJDUDEA-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139452   

TargetMetabotropic glutamate receptor 5(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139452(CHEMBL3764943)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]M-MPEP from recombinant human mGluR5a expressed in human A18 cell membrane homogenate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139452(CHEMBL3764943)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]MPEP from rat mGlu5 receptor expressed in rat cerebrocortical membrane measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139452(CHEMBL3764943)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2019
Entry Details Article
PubMed