BDBM50139466 CHEMBL3765154

SMILES COC(=O)[C@H](CCSC)NC(=O)c1sc(NCc2cncn2Cc2ccc(cc2)C#N)c(C#N)c1-c1ccc(Cl)cc1

InChI Key InChIKey=VSWYGCPHPQYBIQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139466   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Cnrs Upr2301

Curated by ChEMBL

LigandBDBM50139466(CHEMBL3765154)Copy SMILESCopy InChI

Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2017
Entry Details Article
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