BDBM50139473 CHEMBL3763689

SMILES CC(C)(C)OC(=O)N(Cc1cncn1Cc1ccc(cc1)C#N)c1sc(C(O)=O)c(c1C#N)-c1ccc(Cl)cc1

InChI Key InChIKey=XRIYELGXTNWKPU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139473   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Cnrs Upr2301

Curated by ChEMBL

LigandBDBM50139473(CHEMBL3763689)Copy SMILESCopy InChI

Affinity DataIC50: 640nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2017
Entry Details Article
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