BDBM50139477 CHEMBL3765776

SMILES CCOC(=O)c1sc(N(Cc2cn(Cc3ccc(cc3)C#N)cn2)C(=O)OC(C)(C)C)c(C#N)c1-c1ccc(Cl)cc1

InChI Key InChIKey=YWCUUZWIODXZPK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139477   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Cnrs Upr2301

Curated by ChEMBL

LigandBDBM50139477(CHEMBL3765776)Copy SMILESCopy InChI

Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2017
Entry Details Article
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