BDBM50139478 CHEMBL3764593

SMILES CC(C)(C)OC(=O)N(Cc1cn(Cc2ccc(cc2)C#N)cn1)c1sc(C(O)=O)c(c1C#N)-c1ccc(Cl)cc1

InChI Key InChIKey=GTSDCDBHALJEJN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139478   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Cnrs Upr2301

Curated by ChEMBL

LigandBDBM50139478(CHEMBL3764593)Copy SMILESCopy InChI

Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant farnesyltransferase using farnesyl pyrophosphate and Dansyl-GCVLS peptide after 15 mins by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2017
Entry Details Article
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