BDBM50139581 4-(5-{[2-(2,4-Dichloro-benzyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile::CHEMBL348772

SMILES Clc1ccc(CN2Cc3ccccc3CC(NCc3cncn3Cc3ccc(cc3)C#N)C2=O)c(Cl)c1

InChI Key InChIKey=XDXQZGILJBYQMV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139581   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Institut De Recherches Servier

Curated by ChEMBL

LigandBDBM50139581(4-(5-{[2-(2,4-Dichloro-benzyl)-3-oxo-2,3,4,5-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 142nMAssay Description:Inhibition of farnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL