BDBM50139585 4-(5-{[2-(3,5-Difluoro-phenyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile::CHEMBL348819

SMILES Fc1cc(F)cc(c1)N1Cc2ccccc2CC(NCc2cncn2Cc2ccc(cc2)C#N)C1=O

InChI Key InChIKey=FQELRMKFQZFXCH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139585   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Institut De Recherches Servier

Curated by ChEMBL

LigandBDBM50139585(4-(5-{[2-(3,5-Difluoro-phenyl)-3-oxo-2,3,4,5-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of farnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL