BDBM50139624 1-(4-bromo-3-(trifluoromethyl)phenyl)-3-(4-(2-(dimethylcarbamoyl)pyridin-4-yloxy)phenyl)urea::4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]-phenoxy}-pyridine-2-carboxylic acid dimethylamide::CHEMBL165209

SMILES CN(C)C(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Br)c(c3)C(F)(F)F)cc2)ccn1

InChI Key InChIKey=RTPVIVPHKVKHCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139624   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139624(4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139624(4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed