BDBM50140598 5-ethyl-2-ethylsulfanyl-3-(4-hydroxybenzyl)-(6aR,9aS)-3,4,5,8-tetrahydrocyclopenta[4,5]imidazo[2,1-b]purin-4-one::CHEMBL282189

SMILES CCSc1nc2N3[C@H]4CCC[C@H]4N=C3N(CC)C(=O)c2n1Cc1ccc(O)cc1

InChI Key InChIKey=IHKDTWVFLBKOPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140598   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50140598(5-ethyl-2-ethylsulfanyl-3-(4-hydroxybenzyl)-(6aR,9...)
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration against human phosphodiesterase 5 (PDE5) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50140598(5-ethyl-2-ethylsulfanyl-3-(4-hydroxybenzyl)-(6aR,9...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed