BDBM50140731 (3aR,7aR)-1-Ethyl-3-[1-(4-isopropyl-cyclohexyl)-piperidin-4-yl]-octahydro-benzoimidazol-2-one::CHEMBL282195

SMILES CCN1[C@@H]2CCCC[C@H]2N(C2CCN(CC2)C2CCC(CC2)C(C)C)C1=O

InChI Key InChIKey=RRSKOVHIQMVZSF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50140731   

TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50140731((3aR,7aR)-1-Ethyl-3-[1-(4-isopropyl-cyclohexyl)-pi...)
Affinity DataKi:  89nMAssay Description:Binding affinity towards Nociceptin/orphanin FQ (N/OFQ) receptor from recombinant HEK293 cell membranes was determined using binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50140731((3aR,7aR)-1-Ethyl-3-[1-(4-isopropyl-cyclohexyl)-pi...)
Affinity DataKi:  421nMAssay Description:Binding affinity towards opioid receptor mu 1 using [3H]- diprenophine as radioligand from membrane preparations of recombinant HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50140731((3aR,7aR)-1-Ethyl-3-[1-(4-isopropyl-cyclohexyl)-pi...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for the opioid receptor kappa 1 binding affinity using membrane preparations from recombinant HEK293 cells with [3H]U-69593 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50140731((3aR,7aR)-1-Ethyl-3-[1-(4-isopropyl-cyclohexyl)-pi...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for the opioid receptor delta 1 binding affinity using membrane preparations from recombinant HEK293 cells with [3H]naltrindole radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed