BDBM50140985 2-(4-Chloro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-acetamide::CHEMBL32225

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cc(NC(=O)Cc2ccc(Cl)cc2)nn1C

InChI Key InChIKey=AZMPUBACSWPBFN-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50140985   

TargetAdenosine receptor A2b(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50140985(2-(4-Chloro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2...)
Affinity DataKi:  28nMAssay Description:Binding affinity of compound for displacement of specific [3H]- DPCPX binding at human A2B receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50140985(2-(4-Chloro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2...)
Affinity DataKi:  28nMAssay Description:Binding affinity of compound for displacement of [3H]DPCPX binding in HEK293 membranes expressing human A2B adenosine receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50140985(2-(4-Chloro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2...)
Affinity DataIC50: 128nMAssay Description:Inhibitory activity against cAMP production in CHO cells transfected with human A2B adenosine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50140985(2-(4-Chloro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2...)
Affinity DataKi:  520nMAssay Description:Displacement of specific [3H]DPCPX binding at human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50140985(2-(4-Chloro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity of compound for displacement of specific [3H]ZM-241385 binding at human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50140985(2-(4-Chloro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity of compound for displacement of specific [3H]MRE3008-F20 binding at human A3 receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed