BDBM50141009 4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-phenylethynyl]-benzoic acid::CHEMBL34293

SMILES COc1ccc(cc1Cc1cnc(N)nc1N)C#Cc1ccc(cc1)C(O)=O

InChI Key InChIKey=PTAXYASOBQJNTL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50141009   

TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141009(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 3.70nMAssay Description:Inhibitory concentration against Mycobacterium avium dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141009(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 340nMAssay Description:Inhibitory concentration against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141009(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory concentration against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141009(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory concentration against dihydrofolate reductace enzyme of Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141009(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 340nMAssay Description:Inhibitory concentration against dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141009(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory concentration against dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141009(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 3.70nMAssay Description:Inhibitory concentration against dihydrofolate reductase of Mycobacterium aviumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141009(4-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory activity against rat dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed