BDBM50141087 6-{4-[2-(4-Dimethylamino-piperidin-1-yl)-ethoxy]-naphthalen-1-yl}-pyridin-2-ylamine::CHEMBL38762

SMILES CN(C)C1CCN(CCOc2ccc(-c3cccc(N)n3)c3ccccc23)CC1

InChI Key InChIKey=GOZHUVSZDFEZQU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50141087   

TargetNitric oxide synthase, brain(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141087(6-{4-[2-(4-Dimethylamino-piperidin-1-yl)-ethoxy]-n...)
Affinity DataIC50: 195nMAssay Description:In vitro inhibition of rat neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141087(6-{4-[2-(4-Dimethylamino-piperidin-1-yl)-ethoxy]-n...)
Affinity DataIC50: 203nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141087(6-{4-[2-(4-Dimethylamino-piperidin-1-yl)-ethoxy]-n...)
Affinity DataIC50: 5.75E+3nMAssay Description:In vitro inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141087(6-{4-[2-(4-Dimethylamino-piperidin-1-yl)-ethoxy]-n...)
Affinity DataIC50: 7.03E+3nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed