BDBM50141145 But-2-ynoic acid [4-(3-chloro-4-fluoro-phenylamino)-3-cyano-quinolin-6-yl]-amide::CHEMBL31876

SMILES CC#CC(=O)Nc1ccc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1

InChI Key InChIKey=GPLSEURFJLQXHR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141145   

TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50141145(But-2-ynoic acid [4-(3-chloro-4-fluoro-phenylamino...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of peptide substrate phosphorylation by epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50141145(But-2-ynoic acid [4-(3-chloro-4-fluoro-phenylamino...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of epidermal growth factor receptor kinase autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed