BDBM50141149 (E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-phenylamino)-3-cyano-[1,7]naphthyridin-6-yl]-amide::CHEMBL31276

SMILES CN(C)C\C=C\C(=O)Nc1cc2c(Nc3cccc(Br)c3)c(cnc2cn1)C#N

InChI Key InChIKey=MFFPMIGCSMORHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141149   

TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50141149((E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-p...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of peptide substrate phosphorylation by epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50141149((E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-p...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of peptide substrate phosphorylation by epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed