BDBM50141466 (5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-benzyloxy-4-methoxy-phenyl)-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL287517

SMILES COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(OCc2ccccc2)c1

InChI Key InChIKey=PYNCHZOAMKYGTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141466   

TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141466((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-benzyloxy-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141466((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-benzyloxy-...)
Affinity DataIC50: 480nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed