BDBM50141474 (5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-ethoxy-4-methoxy-phenyl)-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL38000

SMILES CCOc1cc(OC)ccc1[C@H]1[C@@H]([C@H](c2ccc(NC(C)C)nc12)c1ccc2OCOc2c1)C(O)=O

InChI Key InChIKey=IGUNGSMXNZWMPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141474   

TargetEndothelin-1 receptor(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141474((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-ethoxy-4-m...)
Affinity DataIC50: 0.740nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50141474((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-ethoxy-4-m...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against [125I]ET1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed