BDBM50141578 (3aR,4R,7R,7aR)-5-(4-But-2-ynyloxy-benzenesulfonyl)-7-hydroxy-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-4-carboxylic acid hydroxyamide::CHEMBL288843

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@H]2OC(C)(C)O[C@@H]2[C@@H]1C(=O)NO

InChI Key InChIKey=RFJSQAZBRWXDMS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50141578   

LigandPNGBDBM50141578((3aR,4R,7R,7aR)-5-(4-But-2-ynyloxy-benzenesulfonyl...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of recombinant human TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50141578((3aR,4R,7R,7aR)-5-(4-But-2-ynyloxy-benzenesulfonyl...)
Affinity DataKi:  58nMAssay Description:Inhibition of recombinant human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50141578((3aR,4R,7R,7aR)-5-(4-But-2-ynyloxy-benzenesulfonyl...)
Affinity DataKi:  118nMAssay Description:Inhibition of recombinant human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50141578((3aR,4R,7R,7aR)-5-(4-But-2-ynyloxy-benzenesulfonyl...)
Affinity DataKi: >850nMAssay Description:Inhibition of recombinant human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed