BDBM50141601 (E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzofuran-2-yl]-but-2-enoic acid::CHEMBL289057

SMILES CCOc1c(cc(cc1-c1cccc2cc(oc12)C(\C)=C\C(O)=O)C(C)C)C(C)C

InChI Key InChIKey=OUHBUMDSRWMXGE-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50141601   

TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141601((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzofu...)
Affinity DataEC50:  74nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoid X receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141601((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzofu...)
Affinity DataKi:  22nMAssay Description:Binding affinity against Retinoic acid receptor RXR-alpha by [3H]9-cis-RA displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Mouse)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141601((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzofu...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against retinoic acid receptor beta by [3H]ATRA displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141601((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzofu...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against retinoic acid receptor alpha by [3H]ATRA displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Mouse)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50141601((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzofu...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against retinoic acid receptor gamma by [3H]ATRA displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed