BDBM50142297 (S)-3-[(2-Ethyl-1,1-dioxo-1,2,3,4,6,7-hexahydro-5,8-dioxa-1lambda*6*-thia-2-aza-anthracene-3-carbonyl)-amino]-2-oxo-4-phenyl-butyric acid methyl ester::CHEMBL8860

SMILES CCN1C(Cc2cc3OCCOc3cc2S1(=O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)OC

InChI Key InChIKey=OQMHERXUKYCBIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142297   

TargetCalpain-1 catalytic subunit(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50142297((S)-3-[(2-Ethyl-1,1-dioxo-1,2,3,4,6,7-hexahydro-5,...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against human calpain 1 in Molt-4 cells (intact human T-cell leukemia cell line)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed