BDBM50142474 7-[(R)-2-((E)-(S)-4-Cyclobutyl-3-hydroxy-but-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid::CHEMBL416262

SMILES O[C@@H](CC1CCC1)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O

InChI Key InChIKey=JLCNNKGBPPDMJV-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142474   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142474(7-[(R)-2-((E)-(S)-4-Cyclobutyl-3-hydroxy-but-1-eny...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142474(7-[(R)-2-((E)-(S)-4-Cyclobutyl-3-hydroxy-but-1-eny...)
Affinity DataEC50:  200nMAssay Description:Agonist activity against recombinant prostanoid EP4 receptor stably transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142474(7-[(R)-2-((E)-(S)-4-Cyclobutyl-3-hydroxy-but-1-eny...)
Affinity DataKi:  5.60E+4nMAssay Description:Binding affinity was determined against prostanoid EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142474(7-[(R)-2-((E)-(S)-4-Cyclobutyl-3-hydroxy-but-1-eny...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity was determined against prostanoid EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed