BDBM50142475 7-{(R)-2-[(E)-3-(3'-Chloro-biphenyl-3-yl)-3-hydroxy-propenyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid::CHEMBL47138

SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O)c1cccc(c1)-c1cccc(Cl)c1

InChI Key InChIKey=HWJIRHWLJWIICT-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142475   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142475(7-{(R)-2-[(E)-3-(3'-Chloro-biphenyl-3-yl)-3-hydrox...)
Affinity DataEC50:  170nMAssay Description:Agonist activity against recombinant prostanoid EP4 receptor stably transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142475(7-{(R)-2-[(E)-3-(3'-Chloro-biphenyl-3-yl)-3-hydrox...)
Affinity DataKi:  420nMAssay Description:Binding affinity was determined against prostanoid EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142475(7-{(R)-2-[(E)-3-(3'-Chloro-biphenyl-3-yl)-3-hydrox...)
Affinity DataKi:  8.50E+4nMAssay Description:Binding affinity was determined against prostanoid EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50142475(7-{(R)-2-[(E)-3-(3'-Chloro-biphenyl-3-yl)-3-hydrox...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity was determined against prostanoid EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed