BDBM50142587 CHEMBL45387::N-{4-[2-(4-Chloro-phenyl)-5-methyl-2H-pyrazol-3-yl]-phenyl}-methanesulfonamide

SMILES Cc1cc(-c2ccc(NS(C)(=O)=O)cc2)n(n1)-c1ccc(Cl)cc1

InChI Key InChIKey=GEUMKTAAPQZMEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142587   

TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142587(N-{4-[2-(4-Chloro-phenyl)-5-methyl-2H-pyrazol-3-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142587(N-{4-[2-(4-Chloro-phenyl)-5-methyl-2H-pyrazol-3-yl...)
Affinity DataIC50: 265nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed