BDBM50142740 (E)-6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-hex-5-enoic acid ethyl ester::CHEMBL48381

SMILES CCOC(=O)C(=O)CC(=O)C=Cc1cccn1Cc1ccccc1

InChI Key InChIKey=MGNPFVTUIUNTGW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142740   

TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50142740((E)-6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-hex-5-en...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibitory activity against HIV-1 integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50142740((E)-6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-hex-5-en...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibitory activity against HIV-1 integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50142740((E)-6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-hex-5-en...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of strand transfer activity of recombinant HIV1 integrase using 5'-end-labeled 21-mer double-stranded DNA as substrate after 60 mins by el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed