BDBM50142744 (E)-6-[1-(4-Methoxy-benzyl)-1H-pyrrol-2-yl]-2,4-dioxo-hex-5-enoic acid ethyl ester::CHEMBL49473

SMILES CCOC(=O)C(=O)CC(=O)C=Cc1cccn1Cc1ccc(OC)cc1

InChI Key InChIKey=QJMATYWDNXVPFU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142744   

TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50142744((E)-6-[1-(4-Methoxy-benzyl)-1H-pyrrol-2-yl]-2,4-di...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibitory activity against HIV-1 integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50142744((E)-6-[1-(4-Methoxy-benzyl)-1H-pyrrol-2-yl]-2,4-di...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibitory activity against HIV-1 integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50142744((E)-6-[1-(4-Methoxy-benzyl)-1H-pyrrol-2-yl]-2,4-di...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of strand transfer activity of recombinant HIV1 integrase using 5'-end-labeled 21-mer double-stranded DNA as substrate after 60 mins by el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50142744((E)-6-[1-(4-Methoxy-benzyl)-1H-pyrrol-2-yl]-2,4-di...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of RNase H activity of recombinant HIV1 reverse transcriptase using poly(dC)-[3H]poly(rG) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed